Microwave-assisted synthesis of thermo- and pH-responsive antitumor drug carrier through reversible addition–fragmentation chain transfer polymerization
نویسندگان
چکیده
منابع مشابه
Synthesis of Star Poly(N-vinylcarbazole) by Microwave-Assisted Reversible Addition-Fragmentation Chain Transfer
Controlled radical polymerization of N-vinylcarbazole (NVK) via microwave-assisted reversible addition-fragmentation chain transfer (RAFT) polymerization is described. As chain transfer agent, 1,3,5-benzyl tri (diethyldithiocarbamate), was used. The chain transfer agent, containing a 1.3.5-trisubstituted benzene ring as core and three dithiocarbamate functionalities attached through an intermed...
متن کاملSynthesis of thiol-linked neoglycopolymers and thermo-responsive glycomicelles as potential drug carrier.
Homopolymer and block copolymer bearing carbohydrate side chain functionality were obtained by grafting glucothiose onto alkene functional scaffolds via a thiol-ene click reaction and the resulting copolymer was used to form thermo-responsive micelles as a potential drug carrier.
متن کاملThermo- and pH-responsive polymers in drug delivery.
Stimuli-responsive polymers show a sharp change in properties upon a small or modest change in environmental condition, e.g. temperature, light, salt concentration or pH. This behaviour can be utilised for the preparation of so-called 'smart' drug delivery systems, which mimic biological response behaviour to a certain extent. The possible environmental conditions to use for this purpose are li...
متن کاملModeling of Reversible Chain Transfer Catalyzed Polymerization by Moment Equations Method
A moment equations method was performed to study the Reversible chain Transfer Catalyzed Polymerization (RTCP) of styrene in 80°C. To do this, a kinetic scheme containing conventional free radical polymerization reactions and equilibrium reactions of RTCP was assumed. After obtaining mass balance equations, three moment equations were defined for free and dormant radicals and dead chains. M...
متن کاملUltra-fast microwave enhanced reversible addition-fragmentation chain transfer (RAFT) polymerization: monomers to polymers in minutes.
Microwave mediated RAFT polymerization leads to ultra-fast polymerizations, whilst keeping excellent control over molecular weights and molecular weight distributions; this is the first example of such a dramatic effect of microwaves on living radical polymerization kinetics, and it shows the potential for chemists to produce very well controlled polymers in a matter of minutes.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Express Polymer Letters
سال: 2017
ISSN: 1788-618X
DOI: 10.3144/expresspolymlett.2017.29